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FBXO2 抗体 (C-Term)

FBXO2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 斑马鱼, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774692
发货至: 中国
  • 抗原 See all FBXO2 抗体
    FBXO2 (F-Box Protein 2 (FBXO2))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 斑马鱼, 兔
    宿主
    • 38
    • 4
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO2 antibody is un-conjugated
    应用范围
    • 41
    • 19
    • 14
    • 13
    • 13
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    LAEFATGQVA VPEDGSWMEI SHTFIDYGPG VRFVRFEHGG QDSVYWKGWF
    预测反应
    Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 93%, Zebrafish: 77%
    产品特性
    This is a rabbit polyclonal antibody against Fbxo2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product FBXO2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 297 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FBXO2 (F-Box Protein 2 (FBXO2))
    别名
    Fbxo2 (FBXO2 产品)
    别名
    FBG1 antibody, FBX2 antibody, Fbs1 antibody, NFB42 antibody, OCP1 antibody, Fbs2 antibody, Prpl4 antibody, F-box protein 2 antibody, FBXO2 antibody, Fbxo2 antibody
    背景
    Fbxo2 is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
    Alias Symbols: FBG1, FBX2, Fbs1, Fbs2, MGC54895, NFB42, Prpl4
    Protein Interaction Partner: Stat1, Cul1, Skp1a, Bace1, Vcp,
    Protein Size: 297
    分子量
    34 kDa
    基因ID
    230904
    NCBI登录号
    NM_176848, NP_789818
    UniProt
    Q80UW2
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