FBXO2 抗体 (C-Term)
Quick Overview for FBXO2 抗体 (C-Term) (ABIN2774692)
抗原
See all FBXO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LAEFATGQVA VPEDGSWMEI SHTFIDYGPG VRFVRFEHGG QDSVYWKGWF
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预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 93%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against Fbxo2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-F-Box Protein 2 (FBXO2) (AA 1-296) antibody
FBXO2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 2 (FBXO2) (AA 1-296) antibodyFBXO2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-F-Box Protein 2 (FBXO2) (AA 1-296) antibodyFBXO2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 2 (FBXO2) (C-Term) antibodyFBXO2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 2 (FBXO2) (C-Term) antibodyFBXO2 适用: 人, 小鼠, 犬, 马, 豚鼠, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 2 (FBXO2) (AA 1-296) antibodyFBXO2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 2 (FBXO2) (AA 244-271), (C-Term) antibodyFBXO2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB24595 unconjugated
anti-F-Box Protein 2 (FBXO2) (AA 251-279), (C-Term) antibodyFBXO2 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 297 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FBXO2 (F-Box Protein 2 (FBXO2))
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别名
- Fbxo2
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背景
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Fbxo2 is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
Alias Symbols: FBG1, FBX2, Fbs1, Fbs2, MGC54895, NFB42, Prpl4
Protein Interaction Partner: Stat1, Cul1, Skp1a, Bace1, Vcp,
Protein Size: 297 -
分子量
- 34 kDa
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基因ID
- 230904
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NCBI登录号
- NM_176848, NP_789818
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UniProt
- Q80UW2
抗原
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