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SRF 抗体 (N-Term)

The 兔 多克隆 anti-SRF antibody (ABIN2774664) specifically detects SRF in WB 和 ChIP. The antibody is reactive with 人, 小鼠, 大鼠, Pig, 犬, Cow, 兔 和 斑马鱼 samples.
产品编号 ABIN2774664
发货至: 中国
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Quick Overview for SRF 抗体 (N-Term) (ABIN2774664)

抗原

See all SRF 抗体
SRF (Serum Response Factor (SRF))

适用

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人, 小鼠, 大鼠, Pig, 犬, Cow, 兔, 斑马鱼

宿主

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兔

克隆类型

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多克隆

标记

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This SRF antibody is un-conjugated

应用范围

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Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
  • 抗原表位

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    N-Term

    原理

    SRF Antibody - N-terminal region

    序列

    ATGGYGPVSG AVSGAKPGKK TRGRVKIKME FIDNKLRRYT TFSKRKTGIM

    交叉反应

    牛, 犬, 小鸡, 人, 小鼠, 大鼠

    预测反应

    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against SRF. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SRF
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SRF (Serum Response Factor (SRF))

    别名

    SRF

    背景

    Background Information: SRF is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).

    Gene Name: Serum response factor (c-fos serum response element-binding transcription factor)

    Alternative Symbols: MCM1

    Protein Name: Serum response factor

    分子量

    52kDa

    基因ID

    6722

    NCBI登录号

    NP_003122

    UniProt

    P11831
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