ADAR 抗体 (N-Term)
Quick Overview for ADAR 抗体 (N-Term) (ABIN2774648)
抗原
See all ADAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GEGKATTAHD LSGKLGTPKK EINRVLYSLA KKGKLQKEAG TPPLWKIAVS
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against ADAR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ADAR
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1226 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study." in: Journal of affective disorders, Vol. 109, Issue 1-2, pp. 75-82, (2008) (PubMed).
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: "Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study." in: Journal of affective disorders, Vol. 109, Issue 1-2, pp. 75-82, (2008) (PubMed).
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- ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
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别名
- ADAR
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背景
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ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: ADAR1, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88dsRBP, p136, P136, K88DSRBP
Protein Interaction Partner: UBC, SUMO2, SUMO3, STAU1, STAU2, SUMO1, RPA3, RPA2, RPA1, ERG, SUZ12, EED, EZH2, BMI1, RNF2, rev, FBXO6, TARDBP, UBE2I, HDAC9, XPO1, WHSC1, TGM2, SNRPN, SNRPB, UPF1, DHX9, DDX17, HNRNPM, CAND1, CUL3, HNRNPA1, ELAVL1, HDAC5, tat, ADAR, HDLBP,
Protein Size: 1226 -
分子量
- 136 kDa
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基因ID
- 103
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NCBI登录号
- NM_001111, NP_001102
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UniProt
- P55265
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途径
- Protein targeting to Nucleus
抗原
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