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ADAR 抗体 (C-Term)

This anti-ADAR antibody is a 兔 多克隆 antibody detecting ADAR in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 豚鼠, 马 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2774647
发货至: 中国

Quick Overview for ADAR 抗体 (C-Term) (ABIN2774647)

抗原

See all ADAR 抗体
ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

适用

人, 小鼠, 大鼠, 豚鼠, 马, 兔

宿主

  • 81
  • 5
  • 1

克隆类型

  • 73
  • 14
多克隆

标记

  • 37
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This ADAR antibody is un-conjugated

应用范围

  • 57
  • 27
  • 27
  • 22
  • 20
  • 10
  • 10
  • 9
  • 8
  • 6
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 15
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    C-Term

    序列

    RMGFTEVTPV TGASLRRTML LLSRSPEAQP KTLPLTGSTF HDQIAMLSHR

    预测反应

    Guinea Pig: 92%, Horse: 92%, Human: 92%, Mouse: 91%, Rabbit: 92%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ADAR. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human ADAR
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1226 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Pan, Ye, Franco, Li, Yu, Zou, Zhang, Jiao, Lin: "Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study." in: Journal of affective disorders, Vol. 109, Issue 1-2, pp. 75-82, (2008) (PubMed).

  • 抗原

    ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

    别名

    ADAR

    背景

    ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: ADAR1, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88dsRBP, p136, P136, K88DSRBP
    Protein Interaction Partner: UBC, SUMO2, SUMO3, STAU1, STAU2, SUMO1, RPA3, RPA2, RPA1, ERG, SUZ12, EED, EZH2, BMI1, RNF2, rev, FBXO6, TARDBP, UBE2I, HDAC9, XPO1, WHSC1, TGM2, SNRPN, SNRPB, UPF1, DHX9, DDX17, HNRNPM, CAND1, CUL3, HNRNPA1, ELAVL1, HDAC5, tat, ADAR, HDLBP,
    Protein Size: 1226

    分子量

    136 kDa

    基因ID

    103

    NCBI登录号

    NM_001111, NP_001102

    UniProt

    P55265

    途径

    Protein targeting to Nucleus
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