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TPSB2 抗体 (Middle Region)

TPSB2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774583
发货至: 中国
  • 抗原 See all TPSB2 抗体
    TPSB2 (Tryptase beta 2 (TPSB2))
    抗原表位
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 21
    • 18
    • 16
    人, 大鼠
    宿主
    • 43
    • 1
    • 1
    • 1
    克隆类型
    • 43
    • 3
    多克隆
    标记
    • 14
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TPSB2 antibody is un-conjugated
    应用范围
    • 22
    • 21
    • 10
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB)
    序列
    QALQRVGIVG GQEAPRSKWP WQVSLRVHGP YWMHFCGGSL IHPQWVLTAA
    预测反应
    Human: 100%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against TPSB2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human TPSB2
    Top Product
    Discover our top product TPSB2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TPSB2 (Tryptase beta 2 (TPSB2))
    别名
    TPSB2 (TPSB2 产品)
    别名
    TPS2 antibody, tryptaseB antibody, tryptaseC antibody, Mcpt6 antibody, tryptase beta 2 (gene/pseudogene) antibody, tryptase beta 2 antibody, TPSB2 antibody, Tpsb2 antibody
    背景
    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
    Alias Symbols: TPS2, tryptaseB, tryptaseC
    Protein Size: 282
    分子量
    31 kDa
    基因ID
    64499
    NCBI登录号
    NM_003294, NP_003285
    UniProt
    P20231
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