THOC7 抗体 (C-Term)
Quick Overview for THOC7 抗体 (C-Term) (ABIN2774475)
抗原
See all THOC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ELEHLSHIKE SVEDKLELRR KQFHVLLSTI HELQQTLEND EKLSEVEEAQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%
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产品特性
- This is a rabbit polyclonal antibody against THOC7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human THOC7
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anti-THO Complex 7 (THOC7) antibody
THOC7 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 7 (THOC7) (AA 138-166), (C-Term) antibodyTHOC7 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB24932 unconjugated
anti-THO Complex 7 (THOC7) (C-Term) antibodyTHOC7 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 7 (THOC7) (AA 1-204) antibodyTHOC7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 7 (THOC7) antibodyTHOC7 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 204 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- THOC7 (THO Complex 7 (THOC7))
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别名
- THOC7
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背景
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THOC7 is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4.
Alias Symbols: FLJ23445, NIF3L1BP1, fSAP24
Protein Interaction Partner: THOC2, RPA3, RPA2, RPA1, CKAP4, UBC, ZC3H15, TRMT112, PPIP5K2, THOC1, UBE3C, USP13, ZPR1, THOC5, VIM, S100A13, WDR36, ZCRB1, THOC3, ZNF606, THOC6, ALYREF, DDX39B, NIF3L1, CHD3, MED8, GOT2, MED18, MED22,
Protein Size: 204 -
分子量
- 22 kDa
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基因ID
- 80145
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NCBI登录号
- NM_025075, NP_079351
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UniProt
- Q6I9Y2
抗原
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