POF1B 抗体 (C-Term)
Quick Overview for POF1B 抗体 (C-Term) (ABIN2774456)
抗原
See all POF1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- MEKDREICRL RSQLNQYHKD VSKREGSCSD FQFKLHELTS LLEEKDSLIK
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预测反应
- Cow: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against POF1B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human POF1B
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anti-Premature Ovarian Failure, 1B (POF1B) (AA 532-589) antibody
POF1B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Premature Ovarian Failure, 1B (POF1B) (AA 469-518) antibodyPOF1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Premature Ovarian Failure, 1B (POF1B) (AA 330-560) antibodyPOF1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 589 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POF1B (Premature Ovarian Failure, 1B (POF1B))
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别名
- POF1B
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背景
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Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined.
Alias Symbols: FLJ22792, POF, POF2B
Protein Interaction Partner: ESR1, COPS5, UBC, Cdk1, Akap12, Fam134a, Lyplal1, Tpr, UCHL5,
Protein Size: 589 -
分子量
- 65 kDa
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基因ID
- 79983
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NCBI登录号
- NM_024921, NP_079197
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UniProt
- Q8WVV4
抗原
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