LGMN 抗体 (Middle Region)
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- 抗原 See all LGMN 抗体
- LGMN (Legumain (LGMN))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼, 绵羊, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LGMN antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ESSYACYYDE KRSTYLGDWY SVNWMEDSDV EDLTKETLHK QYHLVKSHTN
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against LGMN. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human LGMN
- Top Product
- Discover our top product LGMN Primary Antibody
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anti-Legumain (LGMN) (AA 18-433) antibody
LGMN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 18-435) antibodyLGMN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 201-300) antibodyLGMN 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 18-323) antibodyLGMN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) antibodyLGMN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 199-312) antibodyLGMN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 ELISA 宿主: 小鼠 Monoclonal M1 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 433 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- LGMN (Legumain (LGMN))
- 别名
- LGMN (LGMN 产品)
- 别名
- AEP antibody, LGMN1 antibody, PRSC1 antibody, AI746452 antibody, AU022324 antibody, Prsc1 antibody, MGC64351 antibody, cb173 antibody, cb460 antibody, sb:cb173 antibody, zgc:76953 antibody, wu:fa98g05 antibody, wu:fj92g08 antibody, lgmn antibody, MGC88980 antibody, DELTA VACUOLAR PROCESSING ENZYME antibody, DELTAVPE antibody, delta vacuolar processing enzyme antibody, legumain antibody, legumain L homeolog antibody, delta vacuolar processing enzyme antibody, Legumain antibody, LGMN antibody, Lgmn antibody, lgmn.L antibody, lgmn antibody, DELTA-VPE antibody, MBOO_RS07785 antibody, Odosp_3582 antibody, LOC569153 antibody
- 背景
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This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined.
Alias Symbols: AEP, LGMN1, PRSC1
Protein Interaction Partner: USP17L2, TRAF6, USP17L9P, SUMO1, UBC, NEDD8, LAMC3, ACIN1, IGF2BP3, HNRNPR, FBXO6, ISG15, LGMN,
Protein Size: 433 - 分子量
- 48 kDa
- 基因ID
- 5641
- NCBI登录号
- NM_005606, NP_005597
- UniProt
- Q99538
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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