PDIA3 抗体 (C-Term)
Quick Overview for PDIA3 抗体 (C-Term) (ABIN2774375)
抗原
See all PDIA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- YFSPANKKLN PKKYEGGREL SDFISYLQRE ATNPPVIQEE KPKKKKKAQE
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预测反应
- Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against PDIA3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 505 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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别名
- PDIA3
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背景
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This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Alias Symbols: ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC
Protein Interaction Partner: FUS, UBC, MDM2, SUZ12, ABCE1, RBBP4, RAB1A, PGD, MTAP, MTPN, BCCIP, CNDP2, NANS, DAK, ACOT7, NPEPPS, SLC9A3R1, RPL23, SMS, LDHA, HSPD1, CSE1L, ATP6V1A, ADSS, EGFR, UBD, CANX, CALR, HDAC10, MTOR, EFEMP1, ATF2, COL6A1, CLU, APP, ADAM10, AGRN, DCBLD1, RICTOR
Protein Size: 505 -
分子量
- 56 kDa
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基因ID
- 2923
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NCBI登录号
- NM_005313, NP_005304
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UniProt
- P30101
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途径
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
抗原
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