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Cathepsin L 抗体 (C-Term)

This anti-Cathepsin L antibody is a 兔 多克隆 antibody detecting Cathepsin L in WB. Suitable for 人, 小鼠, 大鼠 和 绵羊.
产品编号 ABIN2774366
发货至: 中国

Quick Overview for Cathepsin L 抗体 (C-Term) (ABIN2774366)

抗原

See all Cathepsin L (CTSL1) 抗体
Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

适用

  • 66
  • 36
  • 34
  • 23
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠, 绵羊

宿主

  • 93
  • 19
  • 2

克隆类型

  • 93
  • 21
多克隆

标记

  • 59
  • 18
  • 9
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cathepsin L antibody is un-conjugated

应用范围

  • 90
  • 42
  • 34
  • 20
  • 20
  • 13
  • 13
  • 10
  • 7
  • 7
  • 3
  • 3
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 13
    • 11
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    GGLDSEESYP YEATEESCKY NPKYSVANDT GFVDIPKQEK ALMKAVATVG

    预测反应

    Human: 100%, Mouse: 77%, Rat: 77%, Sheep: 77%

    产品特性

    This is a rabbit polyclonal antibody against CTSL1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 333 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

    别名

    CTSL1

    背景

    The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: CATL, CTSL, FLJ31037, MEP, CTSL1
    Protein Interaction Partner: SGTA, SERPINB3, BTN3A3, RELB, PPP1CC, APOA1, ALB, UBC, EED, BAG6, GEM, ARSA, SERPINB13, CST3, CST7, CTSC, CSTB, KNG1, PLAU, TG, CD7, CSTA, RXRA, CXCL8, IGFBP3, CD74, GCG, COL18A1, CUX1, CTSL, SLPI,
    Protein Size: 333

    分子量

    36 kDa

    基因ID

    1514

    NCBI登录号

    NM_145918, NP_666023

    UniProt

    P07711

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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