Cathepsin L 抗体 (C-Term)
Quick Overview for Cathepsin L 抗体 (C-Term) (ABIN2774366)
抗原
See all Cathepsin L (CTSL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GGLDSEESYP YEATEESCKY NPKYSVANDT GFVDIPKQEK ALMKAVATVG
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预测反应
- Human: 100%, Mouse: 77%, Rat: 77%, Sheep: 77%
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产品特性
- This is a rabbit polyclonal antibody against CTSL1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 333 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
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别名
- CTSL1
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背景
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The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CATL, CTSL, FLJ31037, MEP, CTSL1
Protein Interaction Partner: SGTA, SERPINB3, BTN3A3, RELB, PPP1CC, APOA1, ALB, UBC, EED, BAG6, GEM, ARSA, SERPINB13, CST3, CST7, CTSC, CSTB, KNG1, PLAU, TG, CD7, CSTA, RXRA, CXCL8, IGFBP3, CD74, GCG, COL18A1, CUX1, CTSL, SLPI,
Protein Size: 333 -
分子量
- 36 kDa
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基因ID
- 1514
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NCBI登录号
- NM_145918, NP_666023
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UniProt
- P07711
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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