PPP1R12A 抗体 (C-Term)
Quick Overview for PPP1R12A 抗体 (C-Term) (ABIN2774306)
抗原
See all PPP1R12A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QDSDENEQEQ QSDTEEGSNK KETQTDSISR YETSSTSAGD RYDSLLGRSG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PPP1R12A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PPP1R12A
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anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (C-Term) antibody
Verified PPP1R12A 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 1-200) antibodyPPP1R12A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 1-40), (N-Term) antibodyPPP1R12A 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (C-Term) antibodyPPP1R12A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pThr696) antibodyPPP1R12A 适用: 人, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pThr853) antibodyPPP1R12A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 481-514), (Ser507) antibodyPPP1R12A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB56872 unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pThr853) antibodyPPP1R12A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 710-970) antibodyPPP1R12A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pSer696) antibodyPPP1R12A 适用: 人, 小鼠, 大鼠, 小鸡, 斑马鱼, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1030 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))
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别名
- PPP1R12A
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背景
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Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase.
Alias Symbols: MBS, MGC133042, MYPT1, M130
Protein Interaction Partner: TP53, UBC, NUAK1, RPA3, RPA2, RPA1, TRIM47, AARSD1, PUS1, P3H1, RPRD1B, XPO5, OSGEP, NSUN2, NUSAP1, TTLL12, NUDT5, ARPC2, ACTR3, CUL1, TPP2, PFDN5, PFDN1, NRD1, PAN2, LATS1, gag, FMNL1, PAXIP1, IDH3G, CDV3, RHOA, LRRK2, ATXN10, SIAH2, FBXO25, ARRB2, ELAVL
Protein Size: 1030 -
分子量
- 113 kDa
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基因ID
- 4659
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NCBI登录号
- NM_002480, NP_002471
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UniProt
- O14974
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途径
- M Phase
抗原
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