INPP5D 抗体 (C-Term)
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- 抗原 See all INPP5D 抗体
- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INPP5D antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PPTPTPRPPL PVKSPAVLHL QHSKGRDYRD NTELPHHGKH RPEEGPPGPL
- 预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against INPP5D. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product INPP5D Primary Antibody
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anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (AA 959-1188) antibody
INPP5D 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 9G11 unconjugated Recombinant Antibody
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (N-Term) antibodyINPP5D 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal SHIP-01 unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1189 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
- 别名
- INPP5D (INPP5D 产品)
- 别名
- INPP5D antibody, 256.t00004 antibody, 13.t00027 antibody, ship antibody, ship1 antibody, AI323613 antibody, SHIP antibody, SHIP-1 antibody, SHIP1 antibody, s-SHIP antibody, SIP-145 antibody, hp51CN antibody, inositol polyphosphate-5-phosphatase D antibody, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 antibody, inositol polyphosphate 5-phosphatase antibody, inositol polyphosphate-5-phosphatase D L homeolog antibody, INPP5D antibody, LOC100446045 antibody, inpp5d antibody, EHI_159880 antibody, EHI_153490 antibody, inpp5d.L antibody, LOC100380693 antibody, Inpp5d antibody
- 背景
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This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: MGC104855, MGC142140, MGC142142, SHIP, SHIP1, SIP-145, hp51CN
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-9, KRTAP10-7, KRT40, KHDRBS3, KRT31, DAB1, SH3KBP1, XIAP, INPPL1, LRRK1, SHC1, PTPN11, UBASH3B, CD2AP, SYK, NCK1, GRB2, CBL, UBC, ARAP1, BCR, CLYBL, MME, EPOR, TRIP10, CD300LF, DOK3, LILRB4, INPP5D, FCGR2B, GAB2, DOK2, GAB1, D
Protein Size: 1189 - 分子量
- 131 kDa
- 基因ID
- 3635
- NCBI登录号
- NM_001017915, NP_001017915
- UniProt
- Q92835
- 途径
- TCR Signaling, BCR Signaling, Warburg Effect
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