INPP5D 抗体 (C-Term)
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北京 101111
Quick Overview for INPP5D 抗体 (C-Term) (ABIN2774303)
抗原
See all INPP5D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- INPP5D Antibody - C-terminal region
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序列
- PPTPTPRPPL PVKSPAVLHL QHSKGRDYRD NTELPHHGKH RPEEGPPGPL
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against INPP5D. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (AA 959-1188) antibody
INPP5D 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1020), (pTyr1022) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 9G11 unconjugated Recombinant Antibody
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (N-Term) antibodyINPP5D 适用: 人 WB, ICC, ICFC 宿主: 小鼠 Monoclonal SHIP-01 unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (AA 770-796) antibodyINPP5D 适用: 人 WB 宿主: 兔 Polyclonal RB17405 unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61033-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
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别名
- INPP5D
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背景
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Background Information: This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene Name: Inositol polyphosphate-5-phosphatase, 145 kDa
Alternative Symbols: SHIP, SHIP1, SHIP-1, hp51CN, SIP-145, p150Ship
Protein Name: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
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分子量
- 134 kDa
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基因ID
- 3635
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NCBI登录号
- NP_001017915
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UniProt
- Q92835
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途径
- TCR Signaling, BCR Signaling, Warburg Effect
抗原
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