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CNTF Receptor alpha 抗体 (C-Term)

CNTFR 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774276
发货至: 中国
  • 抗原 See all CNTF Receptor alpha (CNTFR) 抗体
    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
    抗原表位
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, 绵羊
    宿主
    • 42
    • 2
    • 1
    克隆类型
    • 44
    • 1
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CNTF Receptor alpha antibody is un-conjugated
    应用范围
    • 28
    • 14
    • 14
    • 13
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    VAAHATPWTE EPRHLTTEAQ AAETTTSTTS SLAPPPTTKI CDPGELGSGG
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%
    产品特性
    This is a rabbit polyclonal antibody against CNTFR. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human CNTFR
    Top Product
    Discover our top product CNTFR Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 372 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
    别名
    CNTFR (CNTFR 产品)
    别名
    CNTFR-alpha antibody, CNTFRALPHA antibody, Cntfralpha antibody, cb549 antibody, fj33e02 antibody, sb:cb549 antibody, wu:fj33e02 antibody, si:bz76a6.1 antibody, si:dz248f2.1 antibody, si:rp71-76a6.1 antibody, ciliary neurotrophic factor receptor antibody, ciliary neurotrophic factor receptor L homeolog antibody, CNTFR antibody, cntfr.L antibody, Cntfr antibody, cntfr antibody
    背景
    This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.
    Alias Symbols: MGC1774
    Protein Interaction Partner: HN1L, KRTAP4-12, CLCF1, CRLF1, PLSCR1, APPBP2, IL6ST, LIFR, CNTF,
    Protein Size: 372
    分子量
    41 kDa
    基因ID
    1271
    NCBI登录号
    NM_001842, NP_001833
    UniProt
    P26992
    途径
    JAK/STAT Signaling, Feeding Behaviour
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