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CNTF Receptor alpha 抗体 (C-Term)

This anti-CNTF Receptor alpha antibody is a 兔 多克隆 antibody detecting CNTF Receptor alpha in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 和 绵羊.
产品编号 ABIN2774276
发货至: 中国

Quick Overview for CNTF Receptor alpha 抗体 (C-Term) (ABIN2774276)

抗原

See all CNTF Receptor alpha (CNTFR) 抗体
CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊

宿主

  • 47
  • 2
  • 1

克隆类型

  • 49
  • 1
多克隆

标记

  • 19
  • 3
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  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This CNTF Receptor alpha antibody is un-conjugated

应用范围

  • 33
  • 14
  • 14
  • 14
  • 9
  • 5
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
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    • 1
    • 1
    • 1
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    C-Term

    序列

    VAAHATPWTE EPRHLTTEAQ AAETTTSTTS SLAPPPTTKI CDPGELGSGG

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%

    产品特性

    This is a rabbit polyclonal antibody against CNTFR. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CNTFR
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 372 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

    别名

    CNTFR

    背景

    This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.
    Alias Symbols: MGC1774
    Protein Interaction Partner: HN1L, KRTAP4-12, CLCF1, CRLF1, PLSCR1, APPBP2, IL6ST, LIFR, CNTF,
    Protein Size: 372

    分子量

    41 kDa

    基因ID

    1271

    NCBI登录号

    NM_001842, NP_001833

    UniProt

    P26992

    途径

    JAK/STAT Signaling, Feeding Behaviour
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