Adenylosuccinate Lyase 抗体 (Middle Region)
Quick Overview for Adenylosuccinate Lyase 抗体 (Middle Region) (ABIN2774275)
抗原
See all Adenylosuccinate Lyase (ADSL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RVRDDLRFRG VKGTTGTQAS FLQLFEGDDH KVEQLDKMVT EKAGFKRAFI
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 93%
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产品特性
- This is a rabbit polyclonal antibody against ADSL. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ADSL
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anti-Adenylosuccinate Lyase (ADSL) (AA 1-310) antibody
ADSL 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adenylosuccinate Lyase (ADSL) antibodyADSL 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenylosuccinate Lyase (ADSL) (AA 1-484) antibodyADSL 适用: 人 WB, ELISA, IF, FACS, ICC 宿主: 小鼠 Monoclonal AT16C10 unconjugated
anti-Adenylosuccinate Lyase (ADSL) (AA 1-484) antibodyADSL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenylosuccinate Lyase (ADSL) (AA 188-237) antibodyADSL 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenylosuccinate Lyase (ADSL) (AA 1-310) antibodyADSL 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Adenylosuccinate Lyase (ADSL) antibodyADSL 适用: 人, 大鼠, 犬, 猴 WB, IHC, FACS 宿主: 小鼠 Monoclonal 2D10 unconjugated
anti-Adenylosuccinate Lyase (ADSL) (AA 1-484) antibodyADSL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Adenylosuccinate Lyase (ADSL) antibodyADSL 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 484 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Adenylosuccinate Lyase (ADSL)
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别名
- ADSL
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背景
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Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AMPS, ASASE, ASL
Protein Interaction Partner: CALCOCO2, REL, UBC, PDE12, BTF3L4, NPLOC4, EHD4, UBQLN2, NT5C2, WDR4, PAIP1, PLIN3, SAE1, OXSR1, API5, XPNPEP1, WARS, RAD23B, TWF1, DNAJB1, GTF2I, EIF1AX, DRG2, CTSC, NOV, TYMS, SUMO1, DDA1, USP15, USP4,
Protein Size: 484 -
分子量
- 55 kDa
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基因ID
- 158
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NCBI登录号
- NM_000026, NP_000017
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UniProt
- P30566
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途径
- Ribonucleoside Biosynthetic Process
抗原
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