UBA1 抗体 (N-Term)
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北京 101111
Quick Overview for UBA1 抗体 (N-Term) (ABIN2774233)
抗原
See all UBA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- UBA1 Antibody - N-terminal region
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序列
- MEAGPPGSAR PAEPGPCLSG QRGADHTASA SLQSVAGTEP GRHPQAVAAV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against UBA1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBA1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58687-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 8, pp. 4393-9, (2013) (PubMed).
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- UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))
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别名
- UBA1
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背景
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Background Information: UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Gene Name: Ubiquitin-like modifier activating enzyme 1
Alternative Symbols: A1S9, A1ST, GXP1, UBE1, A1S9T, AMCX1, POC20, SMAX2, UBA1A, UBE1X, VEXAS, CFAP124
Protein Name: Ubiquitin-like modifier-activating enzyme 1
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分子量
- 116kDa
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基因ID
- 7317
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NCBI登录号
- NP_003325
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UniProt
- P22314
抗原
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