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UBA1 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-UBA1 antibody is suitable to detect UBA1 in samples from 人, 大鼠, 小鼠, 犬, Cow, 马, 兔 和 豚鼠. It has been validated for WB.
产品编号 ABIN2774233
发货至: 中国
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Quick Overview for UBA1 抗体 (N-Term) (ABIN2774233)

抗原

See all UBA1 抗体
UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

适用

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人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 豚鼠

宿主

  • 91
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克隆类型

  • 62
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多克隆

标记

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This UBA1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MEAGPPGSAR PAEPGPCLSG QRGADHTASA SLQSVAGTEP GRHPQAVAAV

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against UBA1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human UBA1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1058 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Rogers, Olivier, Meyerholz, Dupuy: "Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 8, pp. 4393-9, (2013) (PubMed).

  • 抗原

    UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

    别名

    UBA1

    背景

    UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
    Alias Symbols: A1S9, A1S9T, A1ST, GXP1, MGC4781, UBA1A, UBE1, UBE1X, AMCX1, POC20, SMAX2
    Protein Interaction Partner: USP5, UBE2D2, UBC, FUS, ISG15, UBTD2, HUWE1, UBE2L3, UBE2D1, SUMO2, CDC34, UBE2K, UBE2W, UBE2R2, UBE2J1, UBE2T, UBE2S, UBE2C, UBE2E3, UBE2H, UBE2G2, UBE2G1, UBE2E2, UBE2E1, UBE2D3, UBE2B, UBE2A, UBI4, MDM2, TRIM25, XPNPEP1, EZR, MC1R, IPO5, FH, CTPS1, ATI
    Protein Size: 1058

    分子量

    116 kDa

    基因ID

    7317

    NCBI登录号

    NM_003334, NP_003325

    UniProt

    P22314
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