COPS4 抗体 (Middle Region)
(1 reference)Quick Overview for COPS4 抗体 (Middle Region) (ABIN2774165)
抗原
See all COPS4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- YKLETYLKIA RLYLEDDDPV QAEAYINRAS LLQNESTNEQ LQIHYKVCYA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against COPS4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human COPS4
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anti-COP9 Signalosome Subunit 4 (COPS4) (AA 1-310) antibody
COPS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 53-102) antibodyCOPS4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 143-192) antibodyCOPS4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig, 斑马鱼, 小鸡, Bat, Hamster, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 406 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
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别名
- COPS4
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背景
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COPS4 is one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC10899, MGC15160, CSN4
Protein Interaction Partner: USHBP1, GPS1, UBC, Skp2, PRMT5, KPNA2, HSP90AB1, EPB41L2, EPB41L1, CAST, WDR77, ENAH, DCAF8, COPS5, STIP1, COPS6, YWHAQ, FOS, COPS8, COPS7A, FBXO6, BAG3, FBXW4, vpr, IRF5, COPS7B, COPS2, COPS3, TOR1AIP2, LRR1, FBXO17, DCAF11, DDA1, RFWD2, KLHL42, GRK5, DD
Protein Size: 406 -
分子量
- 46 kDa
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基因ID
- 51138
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NCBI登录号
- NM_016129, NP_057213
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UniProt
- Q9BT78
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途径
- Cell Division Cycle
抗原
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