BCKDHA 抗体 (N-Term)
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- 抗原 See all BCKDHA 抗体
- BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, 豚鼠, 绵羊, Cow, 马, 斑马鱼, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCKDHA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- NVISGIPIYR VMDRQGQIIN PSEDPHLPKE KVLKLYKSMT LLNTMDRILY
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against BCKDHA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human BCKDHA
- Top Product
- Discover our top product BCKDHA Primary Antibody
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anti-Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA) (AA 268-407) antibody
BCKDHA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA) (AA 347-445) antibodyBCKDHA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA) (AA 362-390), (C-Term) antibodyBCKDHA 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20924 unconjugated
anti-Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA) (AA 1-445) antibodyBCKDHA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA) (AA 71-120) antibodyBCKDHA 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 绵羊, Cow, 马, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA) (AA 276-445) antibodyBCKDHA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 445 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))
- 别名
- BCKDHA (BCKDHA 产品)
- 别名
- wu:fd20d04 antibody, zgc:110049 antibody, BCKDE1A antibody, MSU antibody, MSUD1 antibody, OVD1A antibody, BCKDA antibody, E1a antibody, 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial antibody, branched chain keto acid dehydrogenase E1, alpha polypeptide antibody, 2-oxoisovalerate dehydrogenase alpha subunit (branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A) antibody, branched chain ketoacid dehydrogenase E1, alpha polypeptide antibody, LOC704978 antibody, bckdha antibody, BCKDHA antibody, BckdhA antibody, Bckdha antibody
- 背景
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The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid (BCAA) dehydrogenase complex (BCKD, EC 1.2.4.4), an inner-mitochondrial enzyme complex that catalyzes the oxidative decarboxylation of the branched-chain alpha-ketoacids derived from isoleucine, leucine, and valine. This reaction is the second major step in the catabolism of the branched-chain amino acids (Wynn et al., 1998 [PubMed 9582350]). The BCKD complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase (E2, MIM 248610), and a homodimeric dihydrolipoamide dehydrogenase (E3, MIM 238331). E1 is a thiamine pyrophosphate (TPP)-dependent enzyme. The reaction is irreversible and constitutes the first committed step in BCAA oxidation. The BCKDHB gene (MIM 248611) encodes the beta subunit of E1. The complex also contains 2 regulatory enzymes, a kinase and a phosphorylase.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-675 BI910860.1 12-686 676-1196 BG742673.1 80-600 1197-1731 BM702667.1 48-582 1732-1763 BE223026.1 1-32 c 1764-1781 BQ018849.1 1-18 c
Alias Symbols: FLJ45695, MSU, MSUD1, OVD1A, BCKDE1A
Protein Interaction Partner: UBC, CUL3, BCKDHB, BCKDK,
Protein Size: 445 - 分子量
- 50 kDa
- 基因ID
- 593
- NCBI登录号
- NM_000709, NP_000700
- UniProt
- P12694
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