Lactate Dehydrogenase A 抗体 (N-Term)
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Quick Overview for Lactate Dehydrogenase A 抗体 (N-Term) (ABIN2774085)
抗原
See all Lactate Dehydrogenase A (LDHA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- LDHA Antibody - N-terminal region
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序列
- ATLKDQLIYN LLKEEQTPQN KITVVGVGAV GMACAISILM KDLADELALV
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预测反应
- Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 93%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against LDHA. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LDHA
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54776-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "α-cyano-4-hydroxycinnamate impairs pancreatic cancer cells by stimulating the p38 signaling pathway." in: Cellular signalling, Vol. 47, pp. 101-108, (2018) (PubMed).
: "Intratumoral heterogeneity of the therapeutical response to gemcitabine and metformin." in: Oncotarget, Vol. 7, Issue 35, pp. 56395-56407, (2018) (PubMed).
: "Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III." in: PLoS genetics, Vol. 3, Issue 11, pp. e212, (2008) (PubMed).
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- Lactate Dehydrogenase A (LDHA)
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别名
- LDHA
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背景
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Background Information: The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
Gene Name: lactate dehydrogenase A
Alternative Symbols: LDHM, GSD11, PIG19, HEL-S-133P
Protein Name: L-lactate dehydrogenase A chain
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分子量
- 37 kDa
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基因ID
- 3939
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NCBI登录号
- NP_005557
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UniProt
- P00338
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途径
- Warburg Effect
抗原
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