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KPNA4 抗体 (N-Term)

This anti-KPNA4 antibody is a 兔 多克隆 antibody detecting KPNA4 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 兔.
产品编号 ABIN2774081
发货至: 中国

Quick Overview for KPNA4 抗体 (N-Term) (ABIN2774081)

抗原

See all KPNA4 抗体
KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔

宿主

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克隆类型

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多克隆

标记

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This KPNA4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    KNKRDEHLLK RRNVPHEDIC EDSDIDGDYR VQNTSLEAIV QNASSDNQGI

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against KPNA4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human KPNA4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 521 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

    别名

    KPNA4

    背景

    The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. KPNA4 shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: IPOA3, MGC12217, MGC26703, QIP1, SRP3
    Protein Interaction Partner: HNRNPC, CYHR1, MAT2B, NUP50, PLAA, HSF1, UBC, LIN28A, rev, KPNA2, ACLY, SOX2, HDAC1, NACC1, CSNK2A1, AICDA, CBX5, APP, CUL3, DAXX, PARD3, ELAVL1, EXO1, CDKN1B, CUL4B, Ranbp2, Mki67, CTCF, MYC, TP53, H3F3A, RCC1, RAC1, RECQL, TGM2, KPNB1, CSE1L, ARRB2,
    Protein Size: 521

    分子量

    58 kDa

    基因ID

    3840

    NCBI登录号

    NM_002268, NP_002259

    UniProt

    O00629

    途径

    Protein targeting to Nucleus
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