USP21 抗体 (N-Term)
Quick Overview for USP21 抗体 (N-Term) (ABIN2774072)
抗原
See all USP21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PLPPRPGPPD ERLKKLELGR GRTSGSRPRG PLRADHGVPL PGSPPPAVAL
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Usp21. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Usp21
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 566 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- USP21 (Ubiquitin Specific Peptidase 21 (USP21))
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别名
- Usp21
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背景
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Usp21 deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Usp21 regulates gene expression via histone H2A deubiquitination. It is also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.
Alias Symbols: ESTM28, Usp16, Usp23, W53272
Protein Interaction Partner: Eed, TGFBR1, ACVR1,
Protein Size: 566 -
分子量
- 62 kDa
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基因ID
- 30941
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NCBI登录号
- NM_013919, NP_038947
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UniProt
- Q9QZL6
抗原
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