FBXL14 抗体 (N-Term)
Quick Overview for FBXL14 抗体 (N-Term) (ABIN2774033)
抗原
See all FBXL14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- WRDAAYHKSV WRGVEAKLHL RRANPSLFPS LQARGIRRVQ ILSLRRSLSY
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预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against FBXL14. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FBXL14
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 418 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FBXL14 (F-Box and Leucine-Rich Repeat Protein 14 (FBXL14))
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别名
- FBXL14
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背景
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FBXL14 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbl14, MGC40195
Protein Interaction Partner: DICER1, HSP90AA1, COPS5, COPS6, CUL1, Snai1,
Protein Size: 418 -
分子量
- 46 kDa
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基因ID
- 144699
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NCBI登录号
- NM_152441, NP_689654
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UniProt
- Q8N1E6
抗原
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