FRS3 抗体 (Middle Region)
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北京 101111
Quick Overview for FRS3 抗体 (Middle Region) (ABIN2774008)
抗原
See all FRS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- FRS3 Antibody - middle region
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序列
- GFPDGEEDET PLQKPTSTRA AIRSHGSFPV PLTRRRGSPR VFNFDFRRPG
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against FRS3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FRS3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52228-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
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别名
- FRS3
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背景
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Background Information: FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Fibroblast growth factor receptor substrate 3
Alternative Symbols: SNT2, FRS2B, SNT-2, FRS2beta, FRS2-beta
Protein Name: Fibroblast growth factor receptor substrate 3
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分子量
- 54kDa
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基因ID
- 10817
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NCBI登录号
- NP_006644
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UniProt
- O43559
抗原
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