FRS3 抗体 (Middle Region)
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北京 101111
Quick Overview for FRS3 抗体 (Middle Region) (ABIN2774008)
抗原
See all FRS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- GFPDGEEDET PLQKPTSTRA AIRSHGSFPV PLTRRRGSPR VFNFDFRRPG
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against FRS3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FRS3
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anti-Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (AA 101-400) antibody
FRS3 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (AA 1-492) antibodyFRS3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (Internal Region) antibodyFRS3 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (Internal Region) antibodyFRS3 适用: 人, 猴 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (AA 359-408) antibodyFRS3 适用: 人, 大鼠, 小鼠, 猴, 犬, 马, 兔, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 492 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
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别名
- FRS3
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背景
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FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FRS2B, FRS2beta, MGC17167, SNT-2, SNT2
Protein Interaction Partner: NOTCH2NL, RFX6, SPERT, ADAMTSL4, SH3KBP1, CD2AP, SPRY2, TRIP6, TCF4, PLSCR1, GATA1, ERBB2, CBL, AES, ELAVL1, RND1, KARS, BMPR2, NTRK2, PRKCI, NTRK1, MAPK1, PTPN11, FGFR1, GRB2,
Protein Size: 492 -
分子量
- 54 kDa
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基因ID
- 10817
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NCBI登录号
- NM_006653, NP_006644
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UniProt
- O43559
抗原
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