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- 抗原 See all MYCNOS products
- MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))
- 抗原表位
- N-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYCNOS antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- WGGETDASNP APALTACCAA EREANVEQGL AGRLLLCNYE RRLVRRCKIA
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MYCNOS. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
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anti-MYCN Opposite Strand/antisense RNA (MYCNOS) antibody
MYCNOS 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 109 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))
- 别名
- MYCNOS (MYCNOS 产品)
- 别名
- MYCN-AS1 antibody, NCYM antibody, NYCM antibody, MYCN opposite strand antibody, MYCNOS antibody
- 背景
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The N-myc oncogene has been implicated in the pathogenesis of a number of human tumors, including childhood neuroblastoma and adult small cell lung cancer. Complementary DNA clones derived from a transcription unit, N-cym, located on the opposite DNA strand to N-myc have been characterized. There is extensive overlap between the 5' ends of the two transcription units. The N-cym gene, which can encode a 109-amino acid protein, is expressed during fetal development, as well as in tumor cell lines containing amplified N-myc loci, where it is expressed at very high levels. Although other examples of overlapping, opposite-strand eukaryotic genes exist, N-myc and N-cym are unique in that they appear to be coregulated in tumor cell lines under basal growth conditions and in response to the differentiating agent retinoic acid. This coregulation suggests that their protein products may be functionally interrelated during normal development and oncogenesis.
Alias Symbols: NCYM, NYCM, MYCN-AS1
Protein Size: 109 - 分子量
- 12 kDa
- 基因ID
- 10408
- NCBI登录号
- NM_006316, NP_006307
- UniProt
- P40205
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