EDAR 抗体 (Middle Region)
Quick Overview for EDAR 抗体 (Middle Region) (ABIN2773948)
抗原
See all EDAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PAPDKQGSPE LCLLSLVHLA REKSATSNKS AGIQSRRKKI LDVYANVCGV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against EDAR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human EDAR
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anti-Ectodysplasin A Receptor (EDAR) (AA 27-170) antibody
EDAR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A Receptor (EDAR) (AA 64-178) antibodyEDAR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ectodysplasin A Receptor (EDAR) (AA 64-178) antibodyEDAR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-Ectodysplasin A Receptor (EDAR) (AA 290-339) antibodyEDAR 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A Receptor (EDAR) antibodyEDAR 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB, ELISA, SPR, Agon 宿主: 小鼠 Monoclonal EDAR12 unconjugated Recombinant Antibody
anti-Ectodysplasin A Receptor (EDAR) (AA 27-187) antibodyEDAR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A Receptor (EDAR) (Middle Region) antibodyEDAR 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 448 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EDAR (Ectodysplasin A Receptor (EDAR))
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别名
- EDAR
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背景
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EDAR is a member of the tumor necrosis factor receptor family. It is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in the gene encoding EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DL, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1
Protein Interaction Partner: Traf2, Traf1, Eda, FADD, TRADD, EDARADD, MAP3K14, TRAF3,
Protein Size: 448 -
分子量
- 48 kDa
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基因ID
- 10913
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NCBI登录号
- NM_022336, NP_071731
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UniProt
- Q9UNE0
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途径
- Tube Formation, Ubiquitin Proteasome Pathway
抗原
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