PRTFDC1 抗体 (Middle Region)
Quick Overview for PRTFDC1 抗体 (Middle Region) (ABIN2773930)
抗原
See all PRTFDC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- MKALLSNIEK YKPNMIKVAS LLVKRTSRSD GFRPDYAGFE IPNLFVVGYA
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预测反应
- Dog: 92%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 77%, Rat: 92%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against PRTFDC1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PRTFDC1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 225 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation." in: Oncogene, Vol. 26, Issue 57, pp. 7921-32, (2007) (PubMed).
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: "PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation." in: Oncogene, Vol. 26, Issue 57, pp. 7921-32, (2007) (PubMed).
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- PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
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别名
- PRTFDC1
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背景
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PRTFDC1 belongs to the purine/pyrimidine phosphoribosyltransferase family. Epigenetic silencing of PRTFDC1 by hypermethylation of the CpG islands leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis.
Alias Symbols: FLJ11888, HHGP
Protein Interaction Partner: LGALS9B, EEF2KMT, MCMBP, GNPDA1, EPM2AIP1, TCL1A, HPRT1, UBC, RTN3, FLAD1, NIF3L1, DTNB, STAT5A, EWSR1,
Protein Size: 225 -
分子量
- 26 kDa
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基因ID
- 56952
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NCBI登录号
- NM_020200, NP_064585
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UniProt
- Q9NRG1
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途径
- Ribonucleoside Biosynthetic Process
抗原
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