PCMT1 抗体 (Middle Region)
Quick Overview for PCMT1 抗体 (Middle Region) (ABIN2773925)
抗原
See all PCMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- APYDAIHVGA AAPVVPQALI DQLKPGGRLI LPVGPAGGNQ MLEQYDKLQD
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预测反应
- Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against PCMT1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PCMT1
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anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 117-225) antibody
PCMT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 117-228) antibodyPCMT1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) antibodyPCMT1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 62-286) antibodyPCMT1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 1-228) antibodyPCMT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G9 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (Internal Region) antibodyPCMT1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 165-227) antibodyPCMT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 18-55) antibodyPCMT1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB56325 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 93-126) antibodyPCMT1 适用: 人 WB 宿主: 兔 Polyclonal RB56324 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 209-258) antibodyPCMT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 227 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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别名
- PCMT1
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背景
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Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PIMT
Protein Interaction Partner: RPIA, HUWE1, AIMP2, TP53, AURKA, UBC, SUMO1, NEDD8, SH3RF2, LMNA, VCAM1, ITGA4, FN1, CFTR, VKORC1, TP53BP1, SDHAF2, NANS, UBE2C, SEC24A, PPIH, ZRANB2, UCHL3, TPM4, SVIL, RRM2, RAD23A, PSMB7, PFDN2, NOTCH2, GDI1, ATP6V1B2, APOE, CUL1, CUL2, CUL3, CDK2, CAN
Protein Size: 227 -
分子量
- 25 kDa
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基因ID
- 5110
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NCBI登录号
- NM_005389, NP_005380
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UniProt
- P22061
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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