TMEM48 抗体 (Middle Region)
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北京 101111
Quick Overview for TMEM48 抗体 (Middle Region) (ABIN2773878)
抗原
See all TMEM48 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- TMEM48 Antibody - middle region
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序列
- PPIIKYLALQ DLMLLSQYSP SRRQEVFSLS QPGGHPHNWT AISRECLNLL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against TMEM48. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TMEM48
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46268-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Heart failure induces significant changes in nuclear pore complex of human cardiomyocytes." in: PLoS ONE, Vol. 7, Issue 11, pp. e48957, (2012) (PubMed).
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- TMEM48 (Transmembrane Protein 48 (TMEM48))
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别名
- TMEM48
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背景
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Background Information: TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
Gene Name: Transmembrane protein 48
Alternative Symbols: NET3, TMEM48
Protein Name: Nucleoporin NDC1
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分子量
- 76 kDa
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基因ID
- 55706
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NCBI登录号
- NP_060557
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UniProt
- Q9BTX1
抗原
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