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NrCAM 抗体 (N-Term)

This anti-NrCAM antibody is a 兔 多克隆 antibody detecting NrCAM in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 和 兔.
产品编号 ABIN2773852
发货至: 中国

Quick Overview for NrCAM 抗体 (N-Term) (ABIN2773852)

抗原

See all NrCAM (NRCAM) 抗体
NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

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克隆类型

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多克隆

标记

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This NrCAM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    NLSDTEFYGA KSSRERPPTF LTPEGNASNK EELRGNVLSL ECIAEGLPTP

    预测反应

    Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against NRCAM. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human NRCAM
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1304 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

    别名

    NRCAM

    背景

    Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM may also play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of its gene have been associated with autism and addiction vulnerability.Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: KIAA0343, MGC138845, MGC138846
    Protein Interaction Partner: LNX1, MAGI3, HSPA12A, MACF1, UBC, NFASC, NRCAM, CNTN2, PTPRB, ANK2,
    Protein Size: 1304

    分子量

    141 kDa

    基因ID

    4897

    NCBI登录号

    NM_001037132, NP_001032209

    UniProt

    Q92823

    途径

    Regulation of Cell Size
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