POR 抗体 (Middle Region)
(1 reference)Quick Overview for POR 抗体 (Middle Region) (ABIN2773843)
抗原
See all POR 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- VVHTDIDAAK VYMGEMGRLK SYENQKPPFD AKNPFLAAVT TNRKLNQGTE
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
-
产品特性
- This is a rabbit polyclonal antibody against POR. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human POR
-
-
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 77-518) antibody
POR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibodyPOR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-250) antibodyPOR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (N-Term) antibodyKO Validated POR 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 2-671) antibodyPOR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibodyPOR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibodyKO Validated POR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 633-668), (C-Term) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 680 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Cytochrome P450 system expression and DNA adduct formation in the liver of Zacco platypus following waterborne benzo(a)pyrene exposure: implications for biomarker determination." in: Environmental toxicology, Vol. 29, Issue 9, pp. 1032-42, (2014) (PubMed).
-
: "Cytochrome P450 system expression and DNA adduct formation in the liver of Zacco platypus following waterborne benzo(a)pyrene exposure: implications for biomarker determination." in: Environmental toxicology, Vol. 29, Issue 9, pp. 1032-42, (2014) (PubMed).
-
- POR (P450 (Cytochrome) Oxidoreductase (POR))
-
别名
- POR
-
背景
-
POR is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this POR gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CPR, CYPOR, DKFZp686G04235, FLJ26468, P450R
Protein Interaction Partner: UBC, CYP2C9, PGRMC1, STAT1, INSIG1, CYP3A4, CYP2E1, CYP2D6, CYP2C19, CYP2A6, CYP1A2, UBD, SUMO2, RABEPK, FANCC, CYB5A, CYP17A1, XRCC6, HMOX1,
Protein Size: 680 -
分子量
- 77 kDa
-
基因ID
- 5447
-
NCBI登录号
- NM_000941, NP_000932
-
UniProt
- Q63HL4
-
途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
-
