CD200R1 抗体 (N-Term)
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北京 101111
Quick Overview for CD200R1 抗体 (N-Term) (ABIN2764056)
抗原
See all CD200R1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人
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产品特性
- Ox2r, Hypocretin receptor type 2,As first published in 1998 by Sakurai et al, the initial neuropeptides Orexin A and Orexin B were shown to be important in the regulation of appetite. Continued research now suggests that these peptides also influence a wide range of physiological and behavioral processes such as increased EFG arousal and wakefulness and locomotor activity. In addition to the orexins , two G-protein coupled receptors, designated orexin receptor-1 and orexin receptor-2, have been identified which presumably mediate the signaling events from these neuropeptides1. Recently orexin receptors have been found to activate extracellular signal-regulated kinases in CHO cells, namely ERK phosporylation, through Ca2+ influx..2. Further studies seem to indicate a mechanism for orexin receptor mediated cell death and suggest a pathway from GPCRs to apoptosis throughthe MAPK pathways.3
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纯化方法
- Antigen Immunoaffiinity Purification
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免疫原
- Synthetic peptide madde to recombinant Human Orexin Receptor Type 2
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亚型
- IgG
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应用备注
- Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Affinity purified polyclonal antibody provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CD200R1 (CD200 Receptor 1 (CD200R1))
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别名
- Orexin Receptor-2
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UniProt
- O43614
抗原
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