Class A basic helix-loop-helix protein 6, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, NeuroD3, bHLHa6, NGN-1,Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. Efficient DNA binding requires dimerization with another bHLH protein. Expression restricted to the embryonic nervous system.
纯化方法
Antigen Immunoaffiinity Purification
免疫原
Synthetic peptide derived from human neurogenin-1 protein.