FBLN3 抗体
Quick Overview for FBLN3 抗体 (ABIN2763849)
抗原
See all FBLN3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
- EGF-containing fibulin-like extracellular matrix protein 1, Extracellular protein S1-5, Fibulin-like protein, EFEMP1,Fibulin-1 is a modular glycoprotein component of elastic extracellular matrix fibers, basement membranes and blood. It can bind calcium, Fibronectin, Laminin, Nidogen and Fibrinogen. Estrogen exposure to ovarian cancer cell lines can upregulate Fibulin-1. Fibulin-2 is abundant in heart, placenta and ovarian tissue and binds several components of the extracelllar matrix including aggrecan, versican and brevican. Fibulin-3, also known as EFEMP1, is a secreted protein. Defects in the gene for Fibulin-3 cause the autosomal dominant disease Doyne honeycomb retinal dystrophy (DHRD, also known as malattia leventinese) which is characterized by yellow-white deposits (drusen) that accumulate under the retinal pigment epithelium. Fibulin-3 is not present at the site of drusen formation in normal eyes. Fibulin-5 is an integrin-binding extracellular matrix protein that mediates endothelial cell adhesion.
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纯化方法
- Antigen Immunoaffiinity Purification
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免疫原
- Synthetic peptide derived from human fibulin-3 protein
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亚型
- IgG
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anti-Fibulin 3 (FBLN3) (AA 119-148), (N-Term) antibody
FBLN3 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22140 unconjugated
anti-Fibulin 3 (FBLN3) (AA 258-493) antibodyFBLN3 适用: 人 WB 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Fibulin 3 (FBLN3) (AA 27-184) antibodyFBLN3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibulin 3 (FBLN3) (AA 26-213) antibodyFBLN3 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Fibulin 3 (FBLN3) (C-Term) antibodyFBLN3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibulin 3 (FBLN3) (AA 1-493) antibodyFBLN3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fibulin 3 (FBLN3) (Middle Region) antibodyFBLN3 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibulin 3 (FBLN3) antibodyFBLN3 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Fibulin 3 (FBLN3) (AA 126-156), (N-Term) antibodyFBLN3 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Fibulin 3 (FBLN3) (AA 258-493) antibodyFBLN3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- FBLN3 (Fibulin 3 (FBLN3))
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别名
- Fibulin-3
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UniProt
- Q12805
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途径
- EGFR Signaling Pathway
抗原
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