CD94 抗体
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北京 101111
Quick Overview for CD94 抗体 (ABIN2749215)
抗原
See all CD94 (KLRD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD94 Purified
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特异性
- The mouse monoclonal antibody HP-3D9 recognizes an extracellular epitope of CD94, a 70 kDa type II transmembrane glycoprotein expressed on NK cells, NK-T cells, and subsets of CD8+ T cells and gamma/delta T cells.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Cultured human NK cells
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亚型
- IgG1 kappa
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anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) (AA 32-179) antibody
KLRD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibodyKLRD1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 1H1 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) (AA 32-179) antibodyKLRD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) (AA 42-168) antibodyKLRD1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibody (PE)KLRD1 适用: 人 FACS 宿主: 小鼠 Monoclonal HP-3D9 PE
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) (C-Term) antibodyKLRD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibodyKLRD1 适用: 人 FACS 宿主: 小鼠 Monoclonal DX22 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibody (FITC)KLRD1 适用: 人 FACS 宿主: 小鼠 Monoclonal HP-3D9 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibody (APC)KLRD1 适用: 人 FACS 宿主: 小鼠 Monoclonal HP-3D9 APC
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibodyKLRD1 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal B-D49 unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets." in: Blood, Vol. 115, Issue 2, pp. 274-81, (2010) (PubMed).
: "Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 6, pp. 3766-74, (2008) (PubMed).
: "The role of lesional T cells in recalcitrant psoriasis during infliximab therapy." in: European journal of dermatology : EJD, Vol. 15, Issue 6, pp. 454-8, (2005) (PubMed).
: "The inhibitory NK cell receptor CD94/NKG2A and the activating receptor CD94/NKG2C bind the top of HLA-E through mostly shared but partly distinct sets of HLA-E residues." in: European journal of immunology, Vol. 34, Issue 1, pp. 81-90, (2004) (PubMed).
: "Disordered expression of inhibitory receptors on the NK1-type natural killer (NK) leukaemic cells from patients with hypersensitivity to mosquito bites." in: Clinical and experimental immunology, Vol. 120, Issue 3, pp. 413-9, (2000) (PubMed).
: "CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes." in: Immunity, Vol. 5, Issue 2, pp. 163-72, (1996) (PubMed).
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: "CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets." in: Blood, Vol. 115, Issue 2, pp. 274-81, (2010) (PubMed).
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- CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))
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别名
- CD94
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背景
- Killer cell lectin like receptor D1,CD94, also known as KLRD1 (killer cell lectin-like receptor D1), is a transmembrane glycoprotein of the C-type lectin family, which forms disulfide-linked heterodimers with NKG2A, B, C, E, H proteins, constituting functionally distinct receptors of NK cells and related cell types. CD94/NKG2A and CD94/NKG2B heterodimers serve as inhibitory, whereas CD94/NKG2C and CD94/NKG2E as activating receptors. The ligand for CD94/NKG2 complexes has been identified as HLA-E. Extent of CD94 expression on NK cell surface can be used to demonstrate their progress through the differentiation process.,KLR-D1, KLRD1, KCLLRD1
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基因ID
- 3824
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UniProt
- Q13241
抗原
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