CD235a/GYPA 抗体 (PE)
(4 references)Quick Overview for CD235a/GYPA 抗体 (PE) (ABIN2749119)
抗原
See all CD235a/GYPA (GYPA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD235a PE
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特异性
- The mouse monoclonal antibody JC159 recognizes an epitope between amino acids 27 and 40 of the extracellular portion of CD235a (glycophorin A), a sialoglycoprotein expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL. The antibody does not react with glycophorin B.
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交叉反应 （详细）
- Human, Rat
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Membrane preparation from splenic hairy cell leukemia
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亚型
- IgG1 kappa
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anti-Glycophorin A (GYPA) (AA 20-91) antibody
GYPA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycophorin A (GYPA) (AA 1-108) antibodyGYPA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycophorin A (GYPA) antibodyGYPA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GYPA-280 unconjugated
anti-Glycophorin A (GYPA) (Internal Region) antibodyGYPA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycophorin A (GYPA) antibody (FITC)GYPA 适用: 人, 大鼠 FACS 宿主: 小鼠 Monoclonal JC159 FITC
anti-Glycophorin A (GYPA) (C-Term) antibodyVerified GYPA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Glycophorin A (GYPA) antibodyGYPA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rGYPA-280 unconjugated Recombinant Antibody
anti-Glycophorin A (GYPA) antibodyGYPA 适用: 人, 大鼠 FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal JC159 unconjugated
anti-Glycophorin A (GYPA) (C-Term) antibodyGYPA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycophorin A (GYPA) (Internal Region) antibodyGYPA 适用: 人, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment." in: Blood, Vol. 121, Issue 8, pp. 1316-25, (2013) (PubMed).
: "Platelets and erythrocyte-bound platelets bind infectious HIV-1 in plasma of chronically infected patients." in: PLoS ONE, Vol. 8, Issue 11, pp. e81002, (2013) (PubMed).
: "Cell-derived microparticles and vascular pregnancy complications: a systematic and comprehensive review." in: Fertility and sterility, Vol. 99, Issue 2, pp. 441-9, (2013) (PubMed).
: "The composition of the mesenchymal stromal cell compartment in human bone marrow changes during development and aging." in: Haematologica, Vol. 97, Issue 2, pp. 179-83, (2012) (PubMed).
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: "Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment." in: Blood, Vol. 121, Issue 8, pp. 1316-25, (2013) (PubMed).
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- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
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别名
- CD235a
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背景
- Glycophorin A (MNS blood group),CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.,Glycophorin A, GYPA, GPA, PAS-2, Sialoglycoprotein alpha, MN sialoglycoprotein, GPSAT, GPErik, MSN blood group
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基因ID
- 2993
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UniProt
- P02724
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途径
- Maintenance of Protein Location
抗原
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