TCR alpha/beta 抗体 (PE)
(11 references)Quick Overview for TCR alpha/beta 抗体 (PE) (ABIN2749096)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Rt TCR alpha/beta PE
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特异性
- The mouse monoclonal R73 recognizes an extracellular epitope TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.
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交叉反应 （详细）
- Non-Human Primates, Rat
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Rat T blasts and erythrocytes
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亚型
- IgG1 kappa
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anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (FITC)
TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 FITC
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibodyTCR alpha/beta 适用: 大鼠, Non-Human Primate FACS, IP, IHC (fro), WB, IHC (p), ICC 宿主: 小鼠 Monoclonal R73 unconjugated
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibodyTCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 unconjugated
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibodyTCR alpha/beta 适用: 大鼠, Non-Human Primate FACS, IP, IHC (fro), WB, IHC (p), Func, ICC 宿主: 小鼠 Monoclonal R73 unconjugated
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (FITC)TCR alpha/beta 适用: 大鼠, Non-Human Primate FACS 宿主: 小鼠 Monoclonal R73 FITC
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (Biotin)TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 Biotin
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (PerCP)TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 PerCP
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (PE)TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 PE
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (APC)TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 APC
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应用备注
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene." in: Physiological genomics, Vol. 38, Issue 1, pp. 89-97, (2009) (PubMed).
: "A CD28 superagonistic antibody elicits 2 functionally distinct waves of T cell activation in rats." in: The Journal of clinical investigation, Vol. 118, Issue 4, pp. 1405-16, (2008) (PubMed).
: "Neonatal castration affects intrathymic kinetics of T-cell differentiation and the spleen T-cell level." in: The Journal of endocrinology, Vol. 192, Issue 3, pp. 669-82, (2007) (PubMed).
: "Characterization of rat CD8+ uveitogenic T cells specific for interphotoreceptor retinal-binding protein 1177-1191." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 4, pp. 2849-54, (2004) (PubMed).
: "Cutting edge: distinct TCR- and CD28-derived signals regulate CD95L, Bcl-xL, and the survival of primary T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 3, pp. 1341-5, (2004) (PubMed).
: "A clinically relevant CTLA4-Ig-based regimen induces chimerism and tolerance to heart grafts." in: The Annals of thoracic surgery, Vol. 72, Issue 4, pp. 1306-10, (2001) (PubMed).
: "Ischemia/reperfusion injury-mediated down-regulation of adenovirus-mediated gene expression in a rat heart transplantation model is inhibited by co-application of a TNFRp55-Ig chimeric construct." in: Gene therapy, Vol. 7, Issue 14, pp. 1238-43, (2000) (PubMed).
: "The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats." in: The American journal of pathology, Vol. 156, Issue 6, pp. 2057-65, (2000) (PubMed).
: "Activation of the heart by donor brain death accelerates acute rejection after transplantation." in: Circulation, Vol. 102, Issue 19, pp. 2426-33, (2000) (PubMed).
: "Negative regulation of rat natural killer cell activity by major histocompatibility complex class I recognition." in: European journal of immunology, Vol. 26, Issue 11, pp. 2582-6, (1997) (PubMed).
: "A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes." in: The Journal of experimental medicine, Vol. 169, Issue 1, pp. 73-86, (1989) (PubMed).
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: "Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene." in: Physiological genomics, Vol. 38, Issue 1, pp. 89-97, (2009) (PubMed).
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- TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
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别名
- TCR alpha/beta
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背景
- The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRA/B
抗原
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