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Integrin Alpha2b 抗体 (PE)

Name: Integrin Alpha2b 抗体 (PE)
Brand: antibodies-online
SKU: ABIN2749067
Availability: OutOfStock

CD41 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal MWReg30 PE

Separation of murine peripheral blood stained using anti-mouse CD41 (MWReg30) PE antibody (concentration in sample 9 μg/mL, red) from unstained murine peripheral blood (blue) in flow cytometry analysis (surface staining). (Integrin Alpha2b 抗体 (PE))

FACS

1 image

(4 references)

产品编号 ABIN2749067

发货至: 中国

Datasheet as PDF

抗原 See all Integrin Alpha2b (CD41) 抗体

Integrin Alpha2b (CD41)
适用
148

30

21

7

6

5

3

3

2

2

2

1

1

1

1

1
小鼠
宿主
100

49

21

1
大鼠
Compatible Secondaries
克隆类型
120

45

1
单克隆
标记
65

18

13

13

6

4

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Integrin Alpha2b antibody is conjugated to PE
应用范围
125

45

30

26

22

21

13

13

10

9

8

5

2

1

1

1

1

1
Flow Cytometry (FACS)

特异性

The rat monoclonal antibody MWReg30 recognizes an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 kDa) and GPIIb beta (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.

交叉反应（详细）

Mouse

纯化方法

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

免疫原

Murine platelets

克隆位点

MWReg30

亚型

IgG1 kappa

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anti-Integrin Alpha2b (CD41) (AA 351-450) antibody
CD41 适用: 人, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 适用: 小鼠 FACS, ELISA, IHC (fro), IP, IHC (p) 宿主: 大鼠 Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 适用: 小鼠 FACS, ELISA, IHC (fro), IP, IHC (p), Func 宿主: 大鼠 Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 适用: 人, Non-Human Primate FACS, IHC (fro) 宿主: 小鼠 Monoclonal HIP2 unconjugated

anti-Integrin Alpha2b (CD41) antibody (Biotin)
CD41 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-06 Biotin

anti-Integrin Alpha2b (CD41) antibody (FITC)
CD41 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-06 FITC

anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibody
CD41 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) (AA 639-887) antibody
CD41 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Flow cytometry: Recommended dilution: 1-5 μg/mL.

说明

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate was purified by size-exclusion chromatography.

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Ramsey, Zhang, Brown, Steensma, Lin, Wu: "Stress-induced hematopoietic failure in the absence of immediate early response gene X-1 (IEX-1, IER3)." in: Haematologica, Vol. 99, Issue 2, pp. 282-91, (2014) (PubMed).

Boisset, Clapes, Van Der Linden, Dzierzak, Robin: "Integrin αIIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta." in: Biology open, Vol. 2, Issue 5, pp. 525-32, (2013) (PubMed).

Brancaleone, Gobbetti, Cenac, le Faouder, Colom, Flower, Vergnolle, Nourshargh, Perretti: "A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation." in: Blood, Vol. 122, Issue 4, pp. 608-17, (2013) (PubMed).

Sullivan, Wang, Tawfik, Luyendyk: "Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 115, Issue 1, pp. 286-94, (2010) (PubMed).
抗原

Integrin Alpha2b (CD41)

别名

CD41 (CD41 产品)

背景

Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,Platelet GPIIb, Integrin alpha-IIb, GPalpha IIb, GPIIb

基因ID

16399

UniProt

Q9QUM0

途径

Integrin Complex