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CD235a/GYPA 抗体

This anti-CD235a/GYPA antibody is a 小鼠 单克隆 antibody detecting CD235a/GYPA in FACS, IHC (p) 和 IHC (fro). Suitable for 人 和 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2749051
发货至: 中国

Quick Overview for CD235a/GYPA 抗体 (ABIN2749051)

抗原

See all CD235a/GYPA (GYPA) 抗体
CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

适用

  • 168
  • 18
  • 8
  • 2
人, 大鼠

宿主

  • 101
  • 72
  • 10
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 109
  • 76
单克隆

标记

  • 70
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  • 9
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  • 6
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  • 5
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  • 5
  • 5
  • 3
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD235a/GYPA antibody is un-conjugated

应用范围

  • 99
  • 80
  • 68
  • 33
  • 33
  • 24
  • 22
  • 17
  • 13
  • 13
  • 11
  • 8
  • 8
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  • 2
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  • 1
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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

JC159
  • 原理

    Anti-Hu CD235a Purified

    特异性

    The mouse monoclonal antibody JC159 recognizes an epitope between amino acids 27 and 40 of the extracellular portion of CD235a (glycophorin A), a sialoglycoprotein expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL. The antibody does not react with glycophorin B.

    交叉反应 (详细)

    Human, Rat

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Membrane preparation from splenic hairy cell leukemia

    亚型

    IgG1 kappa
  • 应用备注

    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL.
    Flow cytometry: Recommended dilution: 1-4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Beck, Jagodzinski, Eller, Thelian, Matyas, Kunz, Alving: "Platelets and erythrocyte-bound platelets bind infectious HIV-1 in plasma of chronically infected patients." in: PLoS ONE, Vol. 8, Issue 11, pp. e81002, (2013) (PubMed).

    Alijotas-Reig, Palacio-Garcia, Llurba, Vilardell-Tarres: "Cell-derived microparticles and vascular pregnancy complications: a systematic and comprehensive review." in: Fertility and sterility, Vol. 99, Issue 2, pp. 441-9, (2013) (PubMed).

    Maijenburg, Kleijer, Vermeul, Mul, van Alphen, van der Schoot, Voermans: "The composition of the mesenchymal stromal cell compartment in human bone marrow changes during development and aging." in: Haematologica, Vol. 97, Issue 2, pp. 179-83, (2012) (PubMed).

  • 抗原

    CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

    别名

    CD235a

    背景

    Glycophorin A (MNS blood group),CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.,Glycophorin A, GYPA, GPA, PAS-2, Sialoglycoprotein alpha, MN sialoglycoprotein, GPSAT, GPErik, MSN blood group

    基因ID

    2993

    UniProt

    P02724

    途径

    Maintenance of Protein Location
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