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PDE4D PKA Site (AA 50-100), (N-Term), (phosphorylated) 抗体

This 兔 多克隆 antibody specifically detects PDE4D PKA Site in ELISA, IHC (p), IP 和 WB. It exhibits reactivity toward 人, 小鼠 和 大鼠. It has been mentioned in 4+ publications
产品编号 ABIN2747156
发货至: 中国
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Quick Overview for PDE4D PKA Site (AA 50-100), (N-Term), (phosphorylated) 抗体 (ABIN2747156)

抗原

PDE4D PKA Site

适用

人, 小鼠, 大鼠

宿主

  • 2

克隆类型

  • 2
多克隆

标记

  • 1
  • 1
非结合性

应用范围

ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
  • 抗原表位

    • 1
    • 1
    • 1
    • 1
    AA 50-100, N-Term, phosphorylated

    纯化方法

    Affinity Purified

    免疫原

    Phosphorylated synthetic peptide selective for PDE4D PKA site taken within amino acid region 50-100 on human PDE4D8 protein.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.57 μg/μL
  • Fu, Kim, Soto, De Arcangelis, DiPilato, Liu, Xu, Shi, Zhang, Xiang: "A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes." in: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 14771-81, (2014) (PubMed).

    Mahavadi, Nalli, Kumar, Hu, Kuemmerle, Grider, Murthy: "Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle." in: American journal of physiology. Cell physiology, Vol. 307, Issue 4, pp. C402-11, (2014) (PubMed).

    Murthy, Sriwai: "Stimulatory phosphorylation of cAMP-specific PDE4D5 by contractile agonists is mediated by PKC-dependent inactivation of protein phosphatase 2A." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 294, Issue 1, pp. G327-35, (2008) (PubMed).

    Zhu, Kelly, Vemavarapu, Thompson, Strada: "Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells." in: Biochemical pharmacology, Vol. 68, Issue 3, pp. 479-91, (2004) (PubMed).

  • 抗原

    PDE4D PKA Site

    UniProt

    Q08499
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