PDE4D PKA Site (AA 50-100), (N-Term), (phosphorylated) 抗体
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Quick Overview for PDE4D PKA Site (AA 50-100), (N-Term), (phosphorylated) 抗体 (ABIN2747156)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-100, N-Term, phosphorylated
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纯化方法
- Affinity Purified
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免疫原
- Phosphorylated synthetic peptide selective for PDE4D PKA site taken within amino acid region 50-100 on human PDE4D8 protein.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.57 μg/μL
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: "A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes." in: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 14771-81, (2014) (PubMed).
: "Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle." in: American journal of physiology. Cell physiology, Vol. 307, Issue 4, pp. C402-11, (2014) (PubMed).
: "Stimulatory phosphorylation of cAMP-specific PDE4D5 by contractile agonists is mediated by PKC-dependent inactivation of protein phosphatase 2A." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 294, Issue 1, pp. G327-35, (2008) (PubMed).
: "Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells." in: Biochemical pharmacology, Vol. 68, Issue 3, pp. 479-91, (2004) (PubMed).
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- PDE4D PKA Site
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UniProt
- Q08499
抗原
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