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PDE3A 抗体

There are 18+ publications for this product available. The 兔 多克隆 anti-PDE3A antibody is suitable to detect PDE3A in samples from 人, 大鼠, 小鼠, 猴 和 非洲爪蟾. It has been validated for WB, IP, ELISA 和 IHC.
产品编号 ABIN2747088
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PDE3A 抗体 (ABIN2747088)

抗原

See all PDE3A 抗体
PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

适用

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人, 大鼠, 小鼠, 猴, 非洲爪蟾

宿主

  • 27
  • 5
  • 3

克隆类型

  • 31
  • 4
多克隆

标记

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  • 4
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  • 1
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This PDE3A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Affinity Purified

    免疫原

    Synthetic peptide selective only for PDE3A variants

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.72 μg/μL
  • Fields, Koschinski, Zaccolo: "Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes." in: Cellular signalling, Vol. 28, Issue 7, pp. 725-32, (2017) (PubMed).

    Yang, Kirton, MacDougall, Boyle, Deuchars, Frater, Ponnambalam, Hardy, White, Calaghan, Peers, Steele: "The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway." in: Science signaling, Vol. 8, Issue 398, pp. ra101, (2016) (PubMed).

    Rajagopal, Nalli, Kumar, Bhattacharya, Hu, Mahavadi, Grider, Murthy: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." in: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).

    Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

    Mahavadi, Nalli, Kumar, Hu, Kuemmerle, Grider, Murthy: "Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle." in: American journal of physiology. Cell physiology, Vol. 307, Issue 4, pp. C402-11, (2014) (PubMed).

    Vang, Housley, Dong, Basole, Ben-Sasson, Kream, Epstein, Clark, Brocke: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." in: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).

    Ückert, Waldkirch, Sonnenberg, Sandner, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human seminal vesicles." in: The journal of sexual medicine, Vol. 8, Issue 11, pp. 3058-65, (2012) (PubMed).

    Nishioka, Nishida, Ariyoshi, Jian, Saiki, Hirano, Nakaya, Sato, Kita, Iwamoto, Hirano, Inoue, Kurose: "Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 31, Issue 10, pp. 2278-86, (2011) (PubMed).

    Dov, Abramovitch, Warwar, Nesher: "Diminished phosphodiesterase-8B potentiates biphasic insulin response to glucose." in: Endocrinology, Vol. 149, Issue 2, pp. 741-8, (2008) (PubMed).

    Dony, Lai, Dumitrascu, Pullamsetti, Savai, Ghofrani, Weissmann, Schudt, Flockerzi, Seeger, Grimminger, Schermuly: "Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition." in: The European respiratory journal, Vol. 31, Issue 3, pp. 599-610, (2008) (PubMed).

    Uckert, Oelke, Stief, Andersson, Jonas, Hedlund: "Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostate." in: European urology, Vol. 49, Issue 4, pp. 740-5, (2007) (PubMed).

    Albrecht, Uckert, Oelke, Andersson, Jonas, Tröger, Hedlund: "Immunohistochemical distribution of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human vagina: a potential forensic value?" in: Journal of forensic and legal medicine, Vol. 14, Issue 5, pp. 270-4, (2007) (PubMed).

    Ückert, Oelke, Albrecht, Stief, Jonas, Hedlund: "Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minora." in: The journal of sexual medicine, Vol. 4, Issue 3, pp. 602-608, (2007) (PubMed).

    Oelke, Hedlund, Albrecht, Ellinghaus, Stief, Jonas, Andersson, Uckert: "Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: immunohistochemical and molecular biology study." in: Urology, Vol. 67, Issue 5, pp. 1111-6, (2006) (PubMed).

    Uckert, Hedlund, Waldkirch, Sohn, Jonas, Andersson, Stief: "Interactions between cGMP- and cAMP-pathways are involved in the regulation of penile smooth muscle tone." in: World journal of urology, Vol. 22, Issue 4, pp. 261-6, (2005) (PubMed).

    Netherton, Maurice: "Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis." in: Molecular pharmacology, Vol. 67, Issue 1, pp. 263-72, (2005) (PubMed).

    Uckert, Oelke, Waldkirch, Stief, Albrecht, Tröger, Jonas, Andersson, Hedlund: "Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves." in: Urology, Vol. 65, Issue 3, pp. 604-10, (2005) (PubMed).

    Mongillo, McSorley, Evellin, Sood, Lissandron, Terrin, Huston, Hannawacker, Lohse, Pozzan, Houslay, Zaccolo: "Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases." in: Circulation research, Vol. 95, Issue 1, pp. 67-75, (2004) (PubMed).

  • 抗原

    PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

    别名

    PDE3A

    NCBI登录号

    NP_000912

    UniProt

    Q14432

    途径

    cAMP Metabolic Process
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