PDE1C 抗体 (N-Term)
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北京 101111
Quick Overview for PDE1C 抗体 (N-Term) (ABIN2747083)
抗原
See all PDE1C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide corresponding to unique amino acid sequence on PDE1C gene.
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亚型
- IgG
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anti-phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (AA 542-634) antibody
PDE1C 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (AA 375-409) antibodyPDE1C 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB53462 unconjugated
anti-phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (AA 431-480) antibodyPDE1C 适用: 人, 小鼠, 大鼠, Cow, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C) (N-Term) antibodyPDE1C 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.75-1.25 μg/μL
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: "Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome." in: Oncotarget, Vol. 8, Issue 8, pp. 13223-13239, (2017) (PubMed).
: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." in: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).
: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." in: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).
: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).
: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).
: "Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells." in: Biochemical pharmacology, Vol. 79, Issue 3, pp. 321-9, (2009) (PubMed).
: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase during ontogenesis of chick retina." in: Journal of neuroscience research, Vol. 86, Issue 5, pp. 1017-23, (2008) (PubMed).
: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).
: "Characterization of inhibitors of phosphodiesterase 1C on a human cellular system." in: The FEBS journal, Vol. 274, Issue 18, pp. 4812-24, (2007) (PubMed).
: "Mammalian sperm phosphodiesterases and their involvement in receptor-mediated cell signaling important for capacitation." in: Molecular reproduction and development, Vol. 71, Issue 4, pp. 495-508, (2006) (PubMed).
: "Subcellular localization and regulation of type-1C and type-5 phosphodiesterases." in: Biochemical and biophysical research communications, Vol. 341, Issue 3, pp. 837-46, (2006) (PubMed).
: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase in adult rat retina." in: Journal of neuroscience research, Vol. 84, Issue 5, pp. 1020-6, (2006) (PubMed).
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: "Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome." in: Oncotarget, Vol. 8, Issue 8, pp. 13223-13239, (2017) (PubMed).
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- PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
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别名
- PDE1C
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NCBI登录号
- XP_004857
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UniProt
- Q14123
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
抗原
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