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AZGP1 抗体

This anti-AZGP1 antibody is a 小鼠 单克隆 antibody detecting AZGP1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN2745583
发货至: 中国

Quick Overview for AZGP1 抗体 (ABIN2745583)

抗原

See all AZGP1 抗体
AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

适用

  • 60
  • 17
  • 9
  • 1
  • 1

宿主

  • 49
  • 31
  • 1
  • 1
小鼠

克隆类型

  • 51
  • 31
单克隆

标记

  • 62
  • 10
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AZGP1 antibody is un-conjugated

应用范围

  • 72
  • 50
  • 36
  • 35
  • 17
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

Zagy-1
  • 特异性

    Recognizes human zinc-alpha-2-glycoprotein.

    交叉反应

    纯度

    >95 % (SDS-PAGE)

    免疫原

    Recombinant human zinc-alpha-2-glycoprotein.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    In PBS containing 10 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • 抗原

    AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

    别名

    ZAG

    背景

    Zinc-alpha-2-glycoprotein (ZAG), first identified in the 1960s, derives its name from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vivo experiments. Due to its expression in and secretion from adipocytes, ZAG is considered an adipokine. Recently the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.

    UniProt

    P25311

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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