VASP 抗体
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- 抗原 See all VASP 抗体
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VASP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 特异性
- Recognizes both the 46 kDa (Ser157 dephospho-) and 50 kDa (Ser157 phospho-) form of human VASP.
- 交叉反应
- 人
- 无交叉反应
- 小鼠, 大鼠
- 交叉反应 （详细）
- Does not cross-react with mouse or rat VASP.
- 组件
- Contains Positive Control: Human platelet protein (500μg) (Prod. No. AG-35T-0001), supplied at 5mg/ml in SDS-stop solution (100mM NaCl, 73mM Tris/HCl pH 6.7, 10mM DTT, 8mM EDTA, 5% [v/v] glycerol, 2% [w/v] SDS, 10μg/ml bromophenol blue sodium salt). Use 5μl (25μg) per lane.
- 免疫原
- Recombinant human VASP fused to a His-tag.
- Top Product
- Discover our top product VASP Primary Antibody
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anti-Vasodilator-Stimulated phosphoprotein (VASP) antibody
VASP 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) antibodyVASP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-100) antibodyVASP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibodyVASP 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibodyVASP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer239) antibodyVASP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-380) antibodyVASP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer239) antibodyVASP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) antibodyVASP 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibodyVASP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Use 5 μL (25 μg) per lane.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Crude serum containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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- 抗原
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
- 别名
- VASP (VASP 产品)
- 别名
- vasp antibody, MGC80889 antibody, wu:fb23b04 antibody, wu:fk84g05 antibody, zgc:110347 antibody, si:dkey-113g17.1 antibody, si:ch211-202c21.1 antibody, DDBDRAFT_0188463 antibody, DDBDRAFT_0229340 antibody, DDB_0188463 antibody, DDB_0229340 antibody, VASP antibody, vasodilator stimulated phosphoprotein S homeolog antibody, vasodilator stimulated phosphoprotein b antibody, protein enabled antibody, vasodilator-stimulated phosphoprotein antibody, vasodilator stimulated phosphoprotein a antibody, vasodilator stimulated phosphoprotein antibody, vasp.S antibody, vaspb antibody, LOC5573842 antibody, CpipJ_CPIJ004706 antibody, CpipJ_CPIJ004707 antibody, vasP antibody, vasp antibody, VASP antibody, vaspa antibody, Vasp antibody
- 背景
- VASP (vasodilator-stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping proteins. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments and it plays a role in actin-based mobility of Listeria monocytogenes in host cells. It regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. VASP phosphorylation is used to monitor the effect of so-called antiplatelet drugs that reduce platelet reactivity and are used to prevent stent thrombosis, strokes and heart attacks in patients. Phosphorylation of VASP at Ser157 causes a mobility shift in SDS gel electrophoresis from 46 to 50 kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity.
- UniProt
- P50552
- 途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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