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LPP 抗体 (AA 1-109)

LPP 适用: 人, 大鼠, Pig WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2745541
发货至: 中国
  • 抗原 See all LPP 抗体
    LPP (Lipoma-preferred partner (LPP))
    抗原表位
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-109
    适用
    • 30
    • 30
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, Pig
    宿主
    • 41
    • 3
    • 1
    克隆类型
    • 40
    • 5
    多克隆
    标记
    • 20
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This LPP antibody is un-conjugated
    应用范围
    • 18
    • 13
    • 13
    • 12
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    特异性
    Recognizes human, rat and pig LPP.
    交叉反应
    人, 猪, 大鼠
    纯化方法
    Antigen affinity purified.
    组件
    Contains Positive Control: Human skin fibroblast protein, supplied at 1mg/ml in SDS (Laemmli) sample buffer. Use 25μl (25μg) per lane for Western blotting.
    免疫原
    Recombinant human lipoma preferred partner (LPP) (aa 1-109).
    Top Product
    Discover our top product LPP Primary Antibody
  • 应用备注
    Use 25 μL (25 μg) per lane for Western blotting.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 0.01 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • 抗原
    LPP (Lipoma-preferred partner (LPP))
    别名
    Lipoma Preferred Partner (LPP 产品)
    别名
    9430020K16Rik antibody, AA959454 antibody, AU024130 antibody, B130055L10Rik antibody, C79715 antibody, D630048H16 antibody, LIM domain containing preferred translocation partner in lipoma antibody, LPP antibody, Lpp antibody
    背景
    Lipoma preferred partner (LPP) is encoded by the preferred fusion partner gene of the high mobility group protein HMGI-C. LPP is frequently affected by chromosomal translocations in a major group of soft tissue lipomas, as well as in a parosteal lipoma and in pulmonary chondroid hamartomas. The resulting fusion proteins comprise three DNA binding domains of HMGI-C fused to two or three C-terminal LIM domains of LPP and a reciprocal product, respectively. Expression of a HMGI-C/LPP fusion protein causes malignant transformation of fibroblasts. Similar to its relatives zyxin and TRIP (thyroid receptor interacting protein 6) / ZRP-1 (zyxin-related protein 1), LPP consists of a N-terminal proline-rich domain followed by three C-terminal LIM domains (double zinc finger structures that are involved in protein-protein interactions). Like the cytoskeletal protein zyxin, LPP localizes to focal adhesions and cell-cell adherens junctions. LPP harbors a nuclear export signal and displays transcriptional activation capacity.
    UniProt
    Q93052
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