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GPX8 抗体 (AA 38-209)

GPX8 适用: Hepatitis C Virus (HCV) WB, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2745532
发货至: 中国
  • 抗原 See all GPX8 抗体
    GPX8 (Glutathione Peroxidase 8 (GPX8))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    AA 38-209
    适用
    • 26
    • 1
    • 1
    Hepatitis C Virus (HCV)
    宿主
    • 24
    • 2
    克隆类型
    • 26
    多克隆
    标记
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    This GPX8 antibody is un-conjugated
    应用范围
    • 21
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC)
    特异性
    Recognizes human GPx8.
    交叉反应
    Hepatitis C Virus (HCV)
    免疫原
    Recombinant GPx8 (human) (aa 38-209) fused to a GST-tag.
    Top Product
    Discover our top product GPX8 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • 抗原
    GPX8 (Glutathione Peroxidase 8 (GPX8))
    别名
    GPx8 (GPX8 产品)
    别名
    RGD1307506 antibody, zgc:56280 antibody, EPLA847 antibody, GPx-8 antibody, GSHPx-8 antibody, UNQ847 antibody, 2310016C16Rik antibody, AU017063 antibody, ATGPX8 antibody, F2K11.16 antibody, F2K11_16 antibody, glutathione peroxidase 8 antibody, glutathione peroxidase 8 antibody, glutathione peroxidase 8 (putative) antibody, Gpx8 antibody, gpx8 antibody, GPX8 antibody
    物质类
    Viral Protein
    背景
    GPxs are glutathione peroxidases involved in balancing the H2O2 homeostasis in signaling cascades. GPxs have been known to catalyze the reduction of H2O2 or organic hydroperoxides to water or the corresponding alcohols, respectively, typically using glutathione (GSH) as reductant. GPx8 (probable glutathione peroxidase 8) is a 209-aa, 24 kDa protein with an N-terminal cytosolic tip, a predicted transmembrane segment and a catalytic domain located in the endoplasmic reticulum (ER) lumen. GPx8 is a CysGPxs with low glutathione peroxidase activity. A recent study identified GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. GPx8 cleavage by NS3-4A occurs at Cys11, removing the cytosolic tip of GPx8 and was observed in different experimental systems as well as in liver biopsies from patients with chronic hepatitis C.
    UniProt
    Q8TED1
    途径
    Thyroid Hormone Synthesis
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