BMF 抗体
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北京 101111
Quick Overview for BMF 抗体 (ABIN2745518)
抗原
See all BMF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human and mouse Bmf.
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交叉反应
- 人, 小鼠
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交叉反应 (详细)
- Detects several cross-reactivity bands of unknown identity in mice by western blot.
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纯度
- >95 % (SDS-PAGE)
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内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
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免疫原
- Recombinant mouse Bmf.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- In PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
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- BMF (Bcl2 Modifying Factor (BMF))
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别名
- Bmf
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背景
- Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.
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UniProt
- Q96LC9
抗原
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