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- 抗原 See all alpha Tubulin (TUBA1) 抗体
- alpha Tubulin (TUBA1)
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适用
- 所有种类
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This alpha Tubulin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC)
- 特异性
- Detects K40 acetylation of alpha-tubulin, signal specifically increased by modification with tubulin acetyl transferase alpha-TAT1.
- 交叉反应
- 所有种类
- 纯度
- >95 % (SDS-PAGE)
- 免疫原
- Tubulin of the Ciliate Euplotes eluted from the 55kDa band of SDS gel.
- 克隆位点
- TEU318
- 亚型
- IgG1
- Top Product
- Discover our top product TUBA1 Primary Antibody
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anti-alpha Tubulin (TUBA1) antibody
TUBA1 适用: 人, 小鼠, Pig, Saccharomyces cerevisiae, Arabidopsis, Nicotiana tabacum, Paramecium, Turkey, Eisenia fetida WB, IHC (p), IP, ICC, FACS 宿主: 小鼠 Monoclonal TU-01 unconjugated
anti-alpha Tubulin (TUBA1) antibody (FITC)TUBA1 适用: 人, 小鼠, Pig, Saccharomyces cerevisiae, Arabidopsis, Nicotiana tabacum, Paramecium, Turkey, Eisenia fetida ICC, FACS 宿主: 小鼠 Monoclonal TU-01 FITC
anti-alpha Tubulin (TUBA1) antibody (Biotin)TUBA1 适用: 人, 小鼠, Pig, Saccharomyces cerevisiae, Arabidopsis, Nicotiana tabacum, Paramecium, Turkey, Eisenia fetida WB, IHC (p), ICC, FACS 宿主: 小鼠 Monoclonal TU-01 Biotin
anti-alpha Tubulin (TUBA1) antibodyTUBA1 适用: 人, 小鼠, 大鼠, Pig, Nicotiana tabacum, 犬 WB, ELISA, IHC (p), IP, ICC 宿主: 小鼠 Monoclonal TU-16 unconjugated
anti-alpha Tubulin (TUBA1) (C-Term) antibodyTUBA1 适用: 人, 小鼠, 大鼠, 小鸡, Cow WB, ELISA, IHC, FM 宿主: 小鼠 Monoclonal 17H11-F10 unconjugated
anti-alpha Tubulin (TUBA1) (Internal Region) antibodyTUBA1 适用: 人, 小鼠, 大鼠, 小鸡, Cow WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-alpha Tubulin (TUBA1) (AA 380-460) antibodyTUBA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-alpha Tubulin (TUBA1) (acLys40) antibodyTUBA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-alpha Tubulin (TUBA1) antibodyTUBA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha Tubulin (TUBA1) antibodyTUBA1 适用: 人, 小鼠, 大鼠, Pig, Cow, Saccharomyces cerevisiae, 猴, Hamster, 犬, 豚鼠, 山羊, Sea Urchin, Amphibian, Kangaroo WB, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal DM1A unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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- 抗原
- alpha Tubulin (TUBA1)
- 别名
- alpha-Tubulin (TUBA1 产品)
- 别名
- Tuba1 antibody, K-ALPHA-1 antibody, Tuba-1 antibody, cb944 antibody, fb22g06 antibody, tuba1 antibody, wu:fb22g06 antibody, Calpha1 antibody, tubulin, alpha 1A antibody, tubulin alpha 1b antibody, tubulin, alpha 1b antibody, tubulin, alpha 1B antibody, Tuba1a antibody, TUBA1B antibody, tuba1b antibody, Tuba1b antibody
- 背景
- Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and beta-tubulin genes, referred to as tubulin isotypes, and the generation of posttranslational modifications (PTMs) on alpha- and beta-tubulin. Tubulin PTMs include the well-known acetylation or phosphorylation, and others that have so far mostly been found on tubulin, detyrosination/tyrosination, polyglutamylation and polyglycylation. These PTMs might have evolved to specifically regulate tubulin and microtubule functions. Tubulin acetylation was discovered on K40 of flagellar alpha-tubulin in Chlamydomonas reinhardtii and is generally enriched on stable microtubules in cells. It is located on the microtubule lumenal surface. As a result of its localization at the inner face of microtubules, K40 acetylation might rather affect the binding of microtubule inner proteins, a poorly characterized family of proteins. Functional experiments in cells have further suggested that K40 acetylation regulates intracellular transport by regulating the traffic of kinesin motors probably by indirect mechanisms. Acetyltransferase alpha-Tat1 (or Mec-17) specifically acetylate alpha-tubulin K40. Acetylation of tubulin by alpha-Tat1 accumulates selectively in stable, long-lived microtubules thus explaining the link between this posttranslational modication and stable microtubules in cells. However, the direct cellular function of K40 acetylation on microtubules is still unclear.
- 途径
- Microtubule Dynamics
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